Vs. Amherst
Williams vs. Amherst, "The Biggest Little Game in America," is the fourth most played rivalry in NCAA football and the most played in Division III.
On November 10, 2007 Williams became the first NCAA Division III school to host ESPN's College GameDay. Williams won 20-0.
Since 1985 combined gatherings of Williams and Amherst alums have been watching "The Biggest Little game in America" via a satellite feed. The 1995 game was shown on ESPN2 and it ended in a scoreless tie on Weston Field due to unusually heavy rains that turned the field into a quagmire.
Beginning in 1996 the game has been seen live on the New England Sports Network as well as via satellite in the nation's largest cities.
Williams currently leads the all-time series: 70-48-5.
| Year | Winner | Location W/A | Score |
| 2008 | Williams | A | 24-23 |
| 2007 | Williams | W | 20-0 |
| 2006 | Williams | A | 37-7 |
| 2005 | Williams | W | 34-23 |
| 2004 | Amherst | A | 13-10 |
| 2003 | Williams | W | 14-10 |
| 2002 | Amherst | A | 45-35 |
| 2001 | Williams | W | 23-20 OT |
| 2000 | Amherst | A | 20-12 |
| 1999 | Williams | W | 10-7 |
| 1998 | Williams | A | 35-16 |
| 1997 | Williams | W | 48-46 |
| 1996 | Williams | A | 19-13 |
| 1995 | Tie | W | 0-0 |
| 1994 | Williams | A | 48-14 |
| 1993 | Williams | W | 31-2 |
| 1992 | Williams | A | 41-6 |
| 1991 | Williams | W | 37-0 |
| 1990 | Williams | A | 46-18 |
| 1989 | Williams | W | 17-14 |
| 1988 | Williams | A | 21-0 |
| 1987 | Williams | W | 25-7 |
| 1986 | Amherst | A | 10-7 |
| 1985 | Amherst | W | 35-20 |
| 1984 | Amherst | A | 23-6 |
| 1983 | Amherst | W | 14-13 |
| 1982 | Amherst | A | 52-26 |
| 1981 | Amherst | W | 21-17 |
| 1980 | Williams | A | 10-3 |
| 1979 | Williams | W | 19-13 |
| 1978 | Williams | A | 7-2 |
| 1977 | Williams | W | 21-13 |
| 1976 | Amherst | A | 16-0 |
| 1975 | Williams | W | 25-6 |
| 1974 | Williams | A | 17-14 |
| 1973 | Williams | W | 30-14 |
| 1972 | Williams | A | 21-12 |
| 1971 | Williams | W | 31-14 |
| 1970 | Amherst | A | 35-7 |
| 1969 | Amherst | W | 56-25 |
| 1968 | Amherst | A | 24-17 |
| 1967 | Williams | W | 14-10 |
| 1966 | Amherst | A | 54-21 |
| 1965 | Amherst | W | 42-8 |
| 1964 | Amherst | A | 20-7 |
| 1963 | Amherst | W | 19-13 |
| 1962 | Amherst | A | 7-0 |
| 1961 | Williams | W | 12-0 |
| 1960 | Amherst | A | 21-26 |
| 1959 | Amherst | W | 13-0 |
| 1958 | Williams | A | 12-7 |
| 1957 | Williams | W | 39-14 |
| 1956 | Williams | A | 27-12 |
| 1955 | Amherst | W | 13-6 |
| 1954 | Amherst | A | 21-14 |
| 1953 | Amherst | W | 28-14 |
| 1952 | Amherst | A | 21-19 |
| 1951 | Williams | W | 40-7 |
| 1950 | Williams | A | 27-13 |
| 1949 | Williams | W | 19-13 |
| 1948 | Amherst | A | 13-7 |
| 1947 | Amherst | W | 14-6 |
| 1946 | Williams | A | 21-13 |
| 1945 | No Game | ||
| 1944 | No Game | ||
| 1943 | No Game | ||
| 1942 | Amherst | A | 12-6 |
| 1941 | Williams | W | 28-26 |
| 1940 | Williams | A | 19-6 |
| 1939 | Williams | W | 16-8 |
| 1938 | Amherst | A | 41-0 |
| 1937 | Amherst | W | 13-6 |
| 1936 | Amherst | A | 14-13 |
| 1935 | Williams | W | 13-0 |
| 1934 | Amherst | A | 19-7 |
| 1933 | Williams | W | 14-0 |
| 1932 | Amherst | A | 31-7 |
| 1931 | Williams | W | 33-7 |
| 1930 | Williams | A | 16-13 |
| 1929 | Williams | W | 19-0 |
| 1928 | Williams | A | 45-15 |
| 1927 | Amherst | W | 7-6 |
| 1926 | Amherst | A | 20-6 |
| 1925 | Amherst | W | 13-7 |
| 1924 | Williams | A | 27-6 |
| 1923 | Williams | W | 23-7 |
| 1922 | Willaims | A | 27-0 |
| 1921 | Williams | W | 20-0 |
| 1920 | Amherst | A | 14-7 |
| 1919 | Williams | W | 30-0 |
| 1918 | Amherst | A | 20-0 |
| 1917 | Williams | W | 20-0 |
| 1916 | Williams | A | 26-0 |
| 1915 | Amherst | W | 31-0 |
| 1914 | Williams | A | 14-6 |
| 1913 | Amherst | W | 10-0 |
| 1912 | Williams | A | 12-0 |
| 1911 | Williams | W | 8-0 |
| 1910 | Amherst | A | 9-0 |
| 1909 | Williams | W | 17-0 |
| 1908 | Amherst | A | 4-0 |
| 1907 | Williams | W | 26-6 |
| 1906 | Tie | A | 0-0 |
| 1905 | Amherst | W | 17-0 |
| 1904 | Amherst | A | 22-6 |
| 1903 | No Game | ||
| 1902 | No Game | ||
| 1901 | Williams | W | 21-5 |
| 1900 | Williams | A | 16-5 |
| 1899 | Williams | W | 38-0 |
| 1898 | Amherst | W | 16-5 |
| 1897 | Tie | A | 6-6 |
| 1896 | Amherst | W | 6-4 |
| 1895 | Amherst | A | 16-4 |
| 1894 | Williams | W | 34-10 |
| 1893 | Williams | A | 30-12 |
| 1892 | Amherst | W | 60-0 |
| 1891 | Tie | A | 0-0 |
| 1890 | Williams | W | 6-0 |
| 1889 | Tie | A | 10-10 |
| 1888 | Williams | A | 53-0 |
| 1887 | Williams | W | 54-0 |
| 1886 | Willaims | W | 30-0 |
| 1886 | Amherst | W | 6-4 |
| 1885 | Williams | W | 57-0 |
| 1885 | Williams | A | 18-5 |
| 1884 | Williams | W | 11-0 |
| 1884 | Williams | A | 15-2 |
